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使用專業研發降溫儀器

■ 世界最先進牙齒超低溫保存專利研發 ■ 提供電磁場 ■ 單一方向磁場導致電子順磁自旋共振效應 ■ 鍵結動能不為零 ■ 水處於過冷態,但不固化 ■ 改變溫度或移除磁場,水分子均勻瞬間地凍結 ■ 不及形成冰晶,而形成均勻



■ 牙周韌帶的完整與活性為牙齒植回成功的最大指標 ■ 經過6個月PF冷凍的牙齒,ALP > 90%,一般冷凍法之ALP < 60% ■ 冷凍後植回之成功率92%,存活率97%
電磁性冷凍技術之延續開發
■ 協助較大組織以玻璃化現象方式冰存 ■ 作用在特殊凍存液以達到玻璃化現象凍存 ■ 替代血清、DMSO等具有異種來源或細胞毒性的成分

細胞、組織、器官 最佳長期冷凍保存法

Dental Stem Cell Technology
■ Dental stem cell is characterized as mesenchymal stem cell
■ It could be Isolated from:
●Primary teeth: Exfoliated deciduous teeth (SHED)
●Permanent teeth: Dental pulp Periodontal ligament Apical papilla
●ermanent teeth After cryopreservation Dental pulp Periodontal ligament
牙髓幹細胞培養

Surface maker identification of dental pulp stem cells

冷凍過後的牙髓幹細胞,經過數代的培養,仍然具CD44/Stro-1表現

Differentiation of dental pulp stem cells

骨填補材與牙齒幹細胞的結合
Bone Tissue Engineering


● Animal model= Lanyu Pig ● Age= 3 months ● Defect size= Φ6mm (full-thickness) ● Harvesting time= 2 months
Results of radiograph (Implanted for 2 months)


Results of histology

Cosmetics: Dermal Filler Implantation
Hydroxyapatite - based Injectable Dermal Fillers

Enhanced dermal filler at early stage & animal study

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